A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon

Francesca Falconi-Agapito; Philippe Selhorst; Xiomara Merino; Fiorella Torres; Johan Michiels; Connie Fernandez; Michael Talledo; Kevin K. Ariën

doi:10.1016/j.ijid.2020.04.087

A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon

Francesca Falconi-Agapito
, Philippe Selhorst
, Xiomara Merino
, Fiorella Torres
, Johan Michiels
, Connie Fernandez
, Michael Talledo
, Kevin K. Ariën

Institute of Tropical Medicine
Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt
Hospital Santa Gema
University of Antwerp

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

We sequenced the envelope gene of dengue virus serotype 2 (DENV-2-E) in samples from an outbreak reported in 2018, in Yurimaguas, Peru. The strain belongs to lineage 2 of the American/Asian genotype. We report a variant with two novel mutations (I379T and V484I) located in domain III of DENV2-E.

Original language	English
Pages (from-to)	136-138
Number of pages	3
Journal	International Journal of Infectious Diseases
Volume	96
DOIs	https://doi.org/10.1016/j.ijid.2020.04.087
State	Published - Jul 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Dengue virus
Domain III
Envelope protein
Genotype
Lineage

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10.1016/j.ijid.2020.04.087

Cite this

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title = "A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon",

abstract = "We sequenced the envelope gene of dengue virus serotype 2 (DENV-2-E) in samples from an outbreak reported in 2018, in Yurimaguas, Peru. The strain belongs to lineage 2 of the American/Asian genotype. We report a variant with two novel mutations (I379T and V484I) located in domain III of DENV2-E.",

keywords = "Dengue virus, Domain III, Envelope protein, Genotype, Lineage",

author = "Francesca Falconi-Agapito and Philippe Selhorst and Xiomara Merino and Fiorella Torres and Johan Michiels and Connie Fernandez and Michael Talledo and Ari{\"e}n, \{Kevin K.\}",

note = "Publisher Copyright: {\textcopyright} 2020 The Author(s)",

year = "2020",

month = jul,

doi = "10.1016/j.ijid.2020.04.087",

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journal = "International Journal of Infectious Diseases",

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TY - JOUR

T1 - A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon

AU - Falconi-Agapito, Francesca

AU - Selhorst, Philippe

AU - Merino, Xiomara

AU - Torres, Fiorella

AU - Michiels, Johan

AU - Fernandez, Connie

AU - Talledo, Michael

AU - Ariën, Kevin K.

PY - 2020/7

Y1 - 2020/7

N2 - We sequenced the envelope gene of dengue virus serotype 2 (DENV-2-E) in samples from an outbreak reported in 2018, in Yurimaguas, Peru. The strain belongs to lineage 2 of the American/Asian genotype. We report a variant with two novel mutations (I379T and V484I) located in domain III of DENV2-E.

AB - We sequenced the envelope gene of dengue virus serotype 2 (DENV-2-E) in samples from an outbreak reported in 2018, in Yurimaguas, Peru. The strain belongs to lineage 2 of the American/Asian genotype. We report a variant with two novel mutations (I379T and V484I) located in domain III of DENV2-E.

KW - Dengue virus

KW - Domain III

KW - Envelope protein

KW - Genotype

KW - Lineage

UR - https://www.scopus.com/pages/publications/85084502342

U2 - 10.1016/j.ijid.2020.04.087

DO - 10.1016/j.ijid.2020.04.087

M3 - Artículo

C2 - 32387448

AN - SCOPUS:85084502342

SN - 1201-9712

VL - 96

SP - 136

EP - 138

JO - International Journal of Infectious Diseases

JF - International Journal of Infectious Diseases

ER -

A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon

Abstract

UN SDGs

Keywords

Access to Document

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