TY - JOUR
T1 - A Review of Chronic Comorbidities in People Living With HIV in Peru
AU - Nolasco, Marleny
AU - Hsieh, Evelyn
AU - Garcia, Patricia J.
AU - Diaz, Monica M.
PY - 2026/1/1
Y1 - 2026/1/1
N2 - BackgroundAdvances in antiretroviral therapy (ART) have extended the life expectancy of people living with HIV (PWH) in Peru, shifting the healthcare focus toward managing chronic non-communicable comorbidities (NCDs). Yet data on NCD burden among aging PWH in Peru are sparse.MethodsWe conducted a scoping review of peer-reviewed studies from PubMed and LILACS, in English or Spanish, that assessed non-AIDS comorbidities in Peruvian adults with HIV.ResultsWe identified 23 studies, all from Lima, mostly cross-sectional or retrospective, involving predominantly male ART patients. Commonly investigated comorbidities included neurocognitive impairment, mental health disorders (especially depression), cardiovascular disease, and metabolic syndrome; bone disease and non-AIDS malignancies were less studied.ConclusionsFindings suggest frequent cognitive, metabolic, and cardiovascular issues among PWH. Yet critical gaps remain: little is known about frailty, disability, or long-term outcomes. Expanded screening, longitudinal studies, and integrated care models are needed to improve long-term health in aging PWH in Peru.
AB - BackgroundAdvances in antiretroviral therapy (ART) have extended the life expectancy of people living with HIV (PWH) in Peru, shifting the healthcare focus toward managing chronic non-communicable comorbidities (NCDs). Yet data on NCD burden among aging PWH in Peru are sparse.MethodsWe conducted a scoping review of peer-reviewed studies from PubMed and LILACS, in English or Spanish, that assessed non-AIDS comorbidities in Peruvian adults with HIV.ResultsWe identified 23 studies, all from Lima, mostly cross-sectional or retrospective, involving predominantly male ART patients. Commonly investigated comorbidities included neurocognitive impairment, mental health disorders (especially depression), cardiovascular disease, and metabolic syndrome; bone disease and non-AIDS malignancies were less studied.ConclusionsFindings suggest frequent cognitive, metabolic, and cardiovascular issues among PWH. Yet critical gaps remain: little is known about frailty, disability, or long-term outcomes. Expanded screening, longitudinal studies, and integrated care models are needed to improve long-term health in aging PWH in Peru.
KW - aging
KW - chronic comorbidities
KW - chronic illness
KW - HIV
KW - Latin America
KW - Peru
UR - https://www.scopus.com/pages/publications/105045581659
U2 - 10.1177/23259582261470497
DO - 10.1177/23259582261470497
M3 - Artículo de revisión
C2 - 42466519
AN - SCOPUS:105045581659
SN - 2325-9574
VL - 25
SP - 23259582261470497
JO - Journal of the International Association of Providers of AIDS Care
JF - Journal of the International Association of Providers of AIDS Care
ER -