A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians

V. Muñoz; M. Sauvain; G. Bourdy; S. Arrázola; J. Callapa; G. Ruiz; J. Choque; E. Deharo

doi:10.1016/S0378-8741(99)00191-9

A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians

V. Muñoz
, M. Sauvain
, G. Bourdy
, S. Arrázola
, J. Callapa
, G. Ruiz
, J. Choque
, E. Deharo

Inst. Boliviano de Biol. de Altura
Inst. Pharmacologie Biol. Struct.-C.
Casilla 9214
Ctro. Invest. Botanico E.

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

A total of 40 plant extracts traditionally used by the Altenos Indians, a native community living between the Andean block and the tropical valleys of Bolivia, were screened for antimalarial activity in vitro on Plasmodium falciparum chloroquine resistant (Indo) strain, and in vivo on rodent malaria Plasmodium vinckei petteri. Eleven extracts displayed good or moderate activity in vivo, and ten extracts good or very good antimalarial activity in vitro. Results of the screening are discussed here, in relation with the traditional use of plants. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original language	English
Pages (from-to)	123-131
Number of pages	9
Journal	Journal of Ethnopharmacology
Volume	71
Issue number	1-2
DOIs	https://doi.org/10.1016/S0378-8741(99)00191-9
State	Published - Jul 2000
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Altenos
Antimalarial agents
Bolivia
Plasmodium
Quechua
Raqaypampenos
Traditional medicine

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10.1016/S0378-8741(99)00191-9

Cite this

Muñoz, V., Sauvain, M., Bourdy, G., Arrázola, S., Callapa, J., Ruiz, G., Choque, J., & Deharo, E. (2000). A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians. Journal of Ethnopharmacology, 71(1-2), 123-131. https://doi.org/10.1016/S0378-8741(99)00191-9

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Muñoz, V, Sauvain, M, Bourdy, G, Arrázola, S, Callapa, J, Ruiz, G, Choque, J & Deharo, E 2000, 'A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians', Journal of Ethnopharmacology, vol. 71, no. 1-2, pp. 123-131. https://doi.org/10.1016/S0378-8741(99)00191-9

TY - JOUR

T1 - A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians

AU - Muñoz, V.

AU - Sauvain, M.

AU - Bourdy, G.

AU - Arrázola, S.

AU - Callapa, J.

AU - Ruiz, G.

AU - Choque, J.

AU - Deharo, E.

PY - 2000/7

Y1 - 2000/7

N2 - A total of 40 plant extracts traditionally used by the Altenos Indians, a native community living between the Andean block and the tropical valleys of Bolivia, were screened for antimalarial activity in vitro on Plasmodium falciparum chloroquine resistant (Indo) strain, and in vivo on rodent malaria Plasmodium vinckei petteri. Eleven extracts displayed good or moderate activity in vivo, and ten extracts good or very good antimalarial activity in vitro. Results of the screening are discussed here, in relation with the traditional use of plants. Copyright (C) 2000 Elsevier Science Ireland Ltd.

AB - A total of 40 plant extracts traditionally used by the Altenos Indians, a native community living between the Andean block and the tropical valleys of Bolivia, were screened for antimalarial activity in vitro on Plasmodium falciparum chloroquine resistant (Indo) strain, and in vivo on rodent malaria Plasmodium vinckei petteri. Eleven extracts displayed good or moderate activity in vivo, and ten extracts good or very good antimalarial activity in vitro. Results of the screening are discussed here, in relation with the traditional use of plants. Copyright (C) 2000 Elsevier Science Ireland Ltd.

KW - Altenos

KW - Antimalarial agents

KW - Bolivia

KW - Plasmodium

KW - Quechua

KW - Raqaypampenos

KW - Traditional medicine

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DO - 10.1016/S0378-8741(99)00191-9

M3 - Artículo

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AN - SCOPUS:0343603536

SN - 0378-8741

VL - 71

SP - 123

EP - 131

JO - Journal of Ethnopharmacology

JF - Journal of Ethnopharmacology

IS - 1-2

ER -

A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians

Abstract

UN SDGs

Keywords

Access to Document

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