Bioactive indole alkaloids from the bark of Uncaria guianensis

Kit K. Lee; Bing Nan Zhou; David G.I. Kingston; Abraham J. Vaisberg; Gerald B. Hammond

doi:10.1055/s-2006-960860

Bioactive indole alkaloids from the bark of Uncaria guianensis

Kit K. Lee
, Bing Nan Zhou
, David G.I. Kingston
, Abraham J. Vaisberg
, Gerald B. Hammond

School of Science and Engineering

Department of Fish and Wildlife Conservation
Univ. of Massachusetts-Dartmouth
University of Massachusetts System

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

Bioassay-guided fractionation of the EtOH extract of the bark of Uncaria guianensis (Aubl.) Gruel (Rubiaceae) using a yeast-based assay for DNA- damaging agents has furnished the two weakly but selectively active indole alkaloids uncarine C (1) and uncarine E (2) as the major bioactive constituents in this assay.

Original language	English
Pages (from-to)	759-760
Number of pages	2
Journal	Planta medica
Volume	65
Issue number	8
DOIs	https://doi.org/10.1055/s-2006-960860
State	Published - Dec 1999

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title = "Bioactive indole alkaloids from the bark of Uncaria guianensis",

abstract = "Bioassay-guided fractionation of the EtOH extract of the bark of Uncaria guianensis (Aubl.) Gruel (Rubiaceae) using a yeast-based assay for DNA- damaging agents has furnished the two weakly but selectively active indole alkaloids uncarine C (1) and uncarine E (2) as the major bioactive constituents in this assay.",

author = "Lee, \{Kit K.\} and Zhou, \{Bing Nan\} and Kingston, \{David G.I.\} and Vaisberg, \{Abraham J.\} and Hammond, \{Gerald B.\}",

year = "1999",

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doi = "10.1055/s-2006-960860",

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T1 - Bioactive indole alkaloids from the bark of Uncaria guianensis

AU - Lee, Kit K.

AU - Zhou, Bing Nan

AU - Kingston, David G.I.

AU - Vaisberg, Abraham J.

AU - Hammond, Gerald B.

PY - 1999/12

Y1 - 1999/12

N2 - Bioassay-guided fractionation of the EtOH extract of the bark of Uncaria guianensis (Aubl.) Gruel (Rubiaceae) using a yeast-based assay for DNA- damaging agents has furnished the two weakly but selectively active indole alkaloids uncarine C (1) and uncarine E (2) as the major bioactive constituents in this assay.

AB - Bioassay-guided fractionation of the EtOH extract of the bark of Uncaria guianensis (Aubl.) Gruel (Rubiaceae) using a yeast-based assay for DNA- damaging agents has furnished the two weakly but selectively active indole alkaloids uncarine C (1) and uncarine E (2) as the major bioactive constituents in this assay.

UR - https://www.scopus.com/pages/publications/0032713578

U2 - 10.1055/s-2006-960860

DO - 10.1055/s-2006-960860

M3 - Artículo

C2 - 10630124

AN - SCOPUS:0032713578

SN - 0032-0943

VL - 65

SP - 759

EP - 760

JO - Planta medica

JF - Planta medica

IS - 8

ER -

Bioactive indole alkaloids from the bark of Uncaria guianensis

Abstract

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