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Bioactive phenolic glycosides from Amburana cearensis

  • José A. Bravo B
  • , Michel Sauvain
  • , Alberto Gimenez T.
  • , Victoria Muñoz O.
  • , Jorgia Callapa
  • , Louisette Le Men-Olivier
  • , Georges Massiot
  • , Catherine Lavaud
  • Inst. Boliviano de Biol. de Altura
  • Universidad Nacional Mayor de San Andrés
  • UPRESA 6013 CNRS, CPCBAI, B.

Research output: Contribution to journalArticlepeer-review

66 Scopus citations

Abstract

Coumarin (1) and two new phenolic glycosides have been isolated from the stem bark of Amburana cearensis, a tree reported in the Chacobo pharmacopoeia to be used against fever-causing diseases. The novel compounds were identified as: 4-(O-β-D-glucopyranosyl)-hydroxy-7-(3',4'-dihydroxy-benzoyl)- benzyl alcohol (2) and 4-(O-β-D-glucopyranosyl)-hydroxy-7-(3'-methoxy-,4'- hydroxy-benzoyl)-benzyl alcohol (3). All three compounds were assayed in vitro for antimalarial, antiprotozoal, antifungal and antibacterial activities.

Original languageEnglish
Pages (from-to)71-74
Number of pages4
JournalPhytochemistry
Volume50
Issue number1
DOIs
StatePublished - 15 Jan 1999
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Amburana cearensis
  • Biological activities
  • Coumarin
  • Leguminosae
  • Phenolic glycosides
  • Stem-bark

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