Case Report of an Extensively Drug-Resistant Klebsiella pneumoniae Infection with Genomic Characterization of the Strain and Review of Similar Cases in the United States

Fiorella Krapp; Egon A. Ozer; Chao Qi; Alan R. Hauser

doi:10.1093/ofid/ofy074

Case Report of an Extensively Drug-Resistant Klebsiella pneumoniae Infection with Genomic Characterization of the Strain and Review of Similar Cases in the United States

Fiorella Krapp
, Egon A. Ozer
, Chao Qi
, Alan R. Hauser

School of Medicine

Division of Infectious Diseases
Department of Pathology
Northwestern University Feinberg School of Medicine

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Reports of extensively drug-resistant and pan-drug-resistant Klebsiella pneumoniae (XDR-KP and PDR-KP) cases are increasing worldwide. Here, we report a case of XDR-KP with an in-depth molecular characterization of resistance genes using whole-genome sequencing, and we review all cases of XDR-KP and PDR-KP reported in the United States to date.

Original language	English
Journal	Open Forum Infectious Diseases
Volume	5
Issue number	5
DOIs	https://doi.org/10.1093/ofid/ofy074
State	Published - 1 May 2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Antibiotic resistance
Extensively drug-resistant
Klebsiella pneumoniae
Resistance genes

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10.1093/ofid/ofy074

Cite this

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title = "Case Report of an Extensively Drug-Resistant Klebsiella pneumoniae Infection with Genomic Characterization of the Strain and Review of Similar Cases in the United States",

abstract = "Reports of extensively drug-resistant and pan-drug-resistant Klebsiella pneumoniae (XDR-KP and PDR-KP) cases are increasing worldwide. Here, we report a case of XDR-KP with an in-depth molecular characterization of resistance genes using whole-genome sequencing, and we review all cases of XDR-KP and PDR-KP reported in the United States to date.",

keywords = "Antibiotic resistance, Extensively drug-resistant, Klebsiella pneumoniae, Resistance genes",

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AU - Ozer, Egon A.

AU - Qi, Chao

AU - Hauser, Alan R.

N1 - Publisher Copyright: © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence

PY - 2018/5/1

Y1 - 2018/5/1

N2 - Reports of extensively drug-resistant and pan-drug-resistant Klebsiella pneumoniae (XDR-KP and PDR-KP) cases are increasing worldwide. Here, we report a case of XDR-KP with an in-depth molecular characterization of resistance genes using whole-genome sequencing, and we review all cases of XDR-KP and PDR-KP reported in the United States to date.

AB - Reports of extensively drug-resistant and pan-drug-resistant Klebsiella pneumoniae (XDR-KP and PDR-KP) cases are increasing worldwide. Here, we report a case of XDR-KP with an in-depth molecular characterization of resistance genes using whole-genome sequencing, and we review all cases of XDR-KP and PDR-KP reported in the United States to date.

KW - Antibiotic resistance

KW - Extensively drug-resistant

KW - Klebsiella pneumoniae

KW - Resistance genes

UR - https://www.scopus.com/pages/publications/85062050011

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DO - 10.1093/ofid/ofy074

M3 - Artículo

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IS - 5

ER -

Case Report of an Extensively Drug-Resistant Klebsiella pneumoniae Infection with Genomic Characterization of the Strain and Review of Similar Cases in the United States

Abstract

UN SDGs

Keywords

Access to Document

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