Changes in plasma IgE levels during complicated and uncomplicated measles virus infections

Diane E. Griffin; Susan J. Cooper; Robert L. Hirsch; Richard T. Johnson; Imelda Lindo de Soriano; Susi Roedenbeck; Abraham Vaisberg

doi:10.1016/0091-6749(85)90703-1

Changes in plasma IgE levels during complicated and uncomplicated measles virus infections

Diane E. Griffin
, Susan J. Cooper
, Robert L. Hirsch
, Richard T. Johnson
, Imelda Lindo de Soriano
, Susi Roedenbeck
, Abraham Vaisberg

School of Science and Engineering

Johns Hopkins University School of Medicine
Universidad Peruana Cayetano Heredia

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

Abstract

Plasma IgE levels were measured in 214 samples from 182 Peruvian patients with acute measles virus infections. Plasma IgE levels were significantly elevated early in infection compared to later time points. Plasma levels of IgG from the same patients rose during the same time period, whereas levels of IgA and IgM did not change. In patients with postmeasles encephalomyelitis, IgE remained elevated longer than it did in patients either with uncomplicated measles or measles complicated by pneumonia. It is proposed that the elevation of IgE is another manifestation of the altered immunoregulatory function in patients with measles.

Original language	English
Pages (from-to)	206-213
Number of pages	8
Journal	The Journal of Allergy and Clinical Immunology
Volume	76
Issue number	2 PART 1
DOIs	https://doi.org/10.1016/0091-6749(85)90703-1
State	Published - Aug 1985

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10.1016/0091-6749(85)90703-1

Cite this

@article{ddfcd9230ec64b9cbdee8041f4a0ab68,

title = "Changes in plasma IgE levels during complicated and uncomplicated measles virus infections",

abstract = "Plasma IgE levels were measured in 214 samples from 182 Peruvian patients with acute measles virus infections. Plasma IgE levels were significantly elevated early in infection compared to later time points. Plasma levels of IgG from the same patients rose during the same time period, whereas levels of IgA and IgM did not change. In patients with postmeasles encephalomyelitis, IgE remained elevated longer than it did in patients either with uncomplicated measles or measles complicated by pneumonia. It is proposed that the elevation of IgE is another manifestation of the altered immunoregulatory function in patients with measles.",

author = "Griffin, \{Diane E.\} and Cooper, \{Susan J.\} and Hirsch, \{Robert L.\} and Johnson, \{Richard T.\} and \{de Soriano\}, \{Imelda Lindo\} and Susi Roedenbeck and Abraham Vaisberg",

year = "1985",

month = aug,

doi = "10.1016/0091-6749(85)90703-1",

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TY - JOUR

T1 - Changes in plasma IgE levels during complicated and uncomplicated measles virus infections

AU - Griffin, Diane E.

AU - Cooper, Susan J.

AU - Hirsch, Robert L.

AU - Johnson, Richard T.

AU - de Soriano, Imelda Lindo

AU - Roedenbeck, Susi

AU - Vaisberg, Abraham

PY - 1985/8

Y1 - 1985/8

N2 - Plasma IgE levels were measured in 214 samples from 182 Peruvian patients with acute measles virus infections. Plasma IgE levels were significantly elevated early in infection compared to later time points. Plasma levels of IgG from the same patients rose during the same time period, whereas levels of IgA and IgM did not change. In patients with postmeasles encephalomyelitis, IgE remained elevated longer than it did in patients either with uncomplicated measles or measles complicated by pneumonia. It is proposed that the elevation of IgE is another manifestation of the altered immunoregulatory function in patients with measles.

AB - Plasma IgE levels were measured in 214 samples from 182 Peruvian patients with acute measles virus infections. Plasma IgE levels were significantly elevated early in infection compared to later time points. Plasma levels of IgG from the same patients rose during the same time period, whereas levels of IgA and IgM did not change. In patients with postmeasles encephalomyelitis, IgE remained elevated longer than it did in patients either with uncomplicated measles or measles complicated by pneumonia. It is proposed that the elevation of IgE is another manifestation of the altered immunoregulatory function in patients with measles.

UR - https://www.scopus.com/pages/publications/0021843563

U2 - 10.1016/0091-6749(85)90703-1

DO - 10.1016/0091-6749(85)90703-1

M3 - Artículo

C2 - 3160758

AN - SCOPUS:0021843563

SN - 0091-6749

VL - 76

SP - 206

EP - 213

JO - The Journal of Allergy and Clinical Immunology

JF - The Journal of Allergy and Clinical Immunology

IS - 2 PART 1

ER -

Changes in plasma IgE levels during complicated and uncomplicated measles virus infections

Abstract

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