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Déterminer l'efficacité du dépistage de routine des cas de tuberculose (TB) par l'examen de la positivité des frottis d'expectoration pour les bacilles acido-résistants en rapport avec la durée de la toux, les caractéristiques des cas suspects de TB examinés et les facteurs des services de santé.Méthode

Translated title of the contribution: Duration of cough, TB suspects' characteristics and service factors determine the yield of smear microscopy
  • Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt
  • Institute of Tropical Medicine

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Summary: Objective To determine the efficiency of routine tuberculosis (TB) case detection by examining sputum smear positivity for acid-fast bacilli in relation to duration of cough, characteristics of TB suspects examined and health service factors.Method We combined patient interviews with routine data from laboratory registers in 6 health care facilities in San Juan de Lurigancho district, Lima, Peru. A TB case was defined as a TB suspect with at least one positive sputum smear. We calculated adjusted odds ratios with 95% confidence intervals for the association between smear positivity and health service and patient's characteristics.Results Smear positivity was 7.3% (321/4376). Of the 4376 adults submitting sputa, 55.3% (2418) reported cough for <14 days. In this group, smear microscopy yielded 3.2% (78/2418) positive results vs. 12.4% (243/1958) in patients coughing for 14 or more days. Having cough for >2 weeks, being referred by health care staff, attending a secondary-level health care facility, male sex and age between 15 and 44 years were independent determinants of smear positivity.Conclusions Routine case detection yields a low proportion of smear-positive cases because of the inclusion of a high proportion of patients without cough or coughing for <2 weeks. Adherence to the national TB control programme guidelines on the selection of TB suspects would have a positive impact on the smear positivity rate, reduce laboratory costs and workload and possibly improve the reading quality of smear microscopy.

Translated title of the contributionDuration of cough, TB suspects' characteristics and service factors determine the yield of smear microscopy
Original languageFrench
Pages (from-to)1475-1480
Number of pages6
JournalTropical Medicine and International Health
Volume15
Issue number12
DOIs
StatePublished - Dec 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Case detection
  • Cough
  • Peru
  • Smear positivity
  • Tuberculosis

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