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Do Subjective Alcohol Screening Tools Correlate with Biomarkers Among High-Risk Transgender Women and Men Who Have Sex with Men in Lima, Peru?

  • M. C. Herrera
  • , K. A. Konda
  • , S. R. Leon
  • , B. Brown
  • , G. M. Calvo
  • , H. J. Salvatierra
  • , C. F. Caceres
  • , J. D. Klausner
  • , R. Deiss
  • University of California
  • University of California San Francisco
  • Partners In Health
  • University of California Riverside
  • Universidad Peruana Cayetano Heredia
  • Health Directorate of Callao
  • University of California

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Alcohol abuse can influence sexual risk behavior; however, its measurement is not straightforward. This study compared self-reported alcohol use, via the AUDIT and CAGE, with levels of phosphatidylethanol (Peth), a phospholipid biomarker that forms with chronic, heavy drinking, among high-risk MSM and TW in Lima, Peru. Chi square, Fisher’s exact, Wilcoxon ranksum tests compared the instruments. Receiver operating curves determined sensitivity and specificity of the self-reported measures. Among 69 MSM and 17 TW, PEth was positive for 86% (95% CI 77–93%) of participants, while 67% reported binge-drinking in the last 2 weeks. The AUDIT classified 25% as hazardous drinkers while CAGE identified 6% as problem drinkers. Self-reported binge drinking was more sensitive than the AUDIT for PEth positivity (71% vs. 27%, p = 0.022). Among high-risk MSM and TW in Lima, validated, self-report measures of alcohol abuse underestimated biological measures. Further research correlating bio-markers and self-reported alcohol abuse measures is needed.

Original languageEnglish
Pages (from-to)253-261
Number of pages9
JournalAIDS and behavior
Volume21
DOIs
StatePublished - 1 Nov 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being
  2. SDG 5 - Gender Equality
    SDG 5 Gender Equality

Keywords

  • Alcohol use
  • HIV
  • Men who have sex with men
  • Peru
  • Phosphatidylethanol

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