ESTUDIO COMPARATIVO: IOMEFLOXACINA VS. TRIMETOPRIM/SULFAMETOXAZOL EN EL TRATAMIENTO DE LA DIARREA AGUDA BACTERIANA DEL ADULTO

E. Gotuzzo; C. Carrillo; J. Echeverria; R. Ruiz; P. Campos

ESTUDIO COMPARATIVO: IOMEFLOXACINA VS. TRIMETOPRIM/SULFAMETOXAZOL EN EL TRATAMIENTO DE LA DIARREA AGUDA BACTERIANA DEL ADULTO

Translated title of the contribution: Lomefloxacine vs. Trimetroprim/Sulfametoxazol for the treatment of bacterial acute diarrhea in the adult

E. Gotuzzo
, C. Carrillo
, J. Echeverria
, R. Ruiz
, P. Campos

Universidad Peruana Cayetano Heredia

Research output: Contribution to journal › Article › peer-review

Abstract

Fifty patients suffering acute bacterial diarrhea were studied under the design of single-blind randomly allocated and prospective. They received orally a single daily dose of 400 mg of lomefloxacin or trimethoprim/sulfamethoxazole 160/800 mg B.I.D. during five days. Evaluation was made in 47 patients: 23 corresponding to lomefloxacin group and 24 for the comparative preparate. Mean duration of diarrhea in the lomefloxacin group was 1.5 days vs 2.0 days in the other therapeutic group (P _ 0.001). Cultures in both groups of patients were negative after 24-48 hours post-treatment. Clinical percentage of success was 100% for lomefloxacin and 96% for those treated with trimethoprim/sulfamethozazol. Mild reactions were reported in 3 and 4 patients of each group respectively.

Translated title of the contribution	Lomefloxacine vs. Trimetroprim/Sulfametoxazol for the treatment of bacterial acute diarrhea in the adult
Original language	Spanish
Pages (from-to)	51-55
Number of pages	5
Journal	Compendium de Investigaciones Clinicas Latinoamericanas
Volume	11
Issue number	2
State	Published - 1991

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title = "ESTUDIO COMPARATIVO: IOMEFLOXACINA VS. TRIMETOPRIM/SULFAMETOXAZOL EN EL TRATAMIENTO DE LA DIARREA AGUDA BACTERIANA DEL ADULTO",

abstract = "Fifty patients suffering acute bacterial diarrhea were studied under the design of single-blind randomly allocated and prospective. They received orally a single daily dose of 400 mg of lomefloxacin or trimethoprim/sulfamethoxazole 160/800 mg B.I.D. during five days. Evaluation was made in 47 patients: 23 corresponding to lomefloxacin group and 24 for the comparative preparate. Mean duration of diarrhea in the lomefloxacin group was 1.5 days vs 2.0 days in the other therapeutic group (P \_ 0.001). Cultures in both groups of patients were negative after 24-48 hours post-treatment. Clinical percentage of success was 100\% for lomefloxacin and 96\% for those treated with trimethoprim/sulfamethozazol. Mild reactions were reported in 3 and 4 patients of each group respectively.",

author = "E. Gotuzzo and C. Carrillo and J. Echeverria and R. Ruiz and P. Campos",

year = "1991",

language = "Espa{\~n}ol",

volume = "11",

pages = "51--55",

journal = "Compendium de Investigaciones Clinicas Latinoamericanas",

issn = "0185-1934",

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TY - JOUR

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T2 - IOMEFLOXACINA VS. TRIMETOPRIM/SULFAMETOXAZOL EN EL TRATAMIENTO DE LA DIARREA AGUDA BACTERIANA DEL ADULTO

AU - Gotuzzo, E.

AU - Carrillo, C.

AU - Echeverria, J.

AU - Ruiz, R.

AU - Campos, P.

PY - 1991

Y1 - 1991

N2 - Fifty patients suffering acute bacterial diarrhea were studied under the design of single-blind randomly allocated and prospective. They received orally a single daily dose of 400 mg of lomefloxacin or trimethoprim/sulfamethoxazole 160/800 mg B.I.D. during five days. Evaluation was made in 47 patients: 23 corresponding to lomefloxacin group and 24 for the comparative preparate. Mean duration of diarrhea in the lomefloxacin group was 1.5 days vs 2.0 days in the other therapeutic group (P _ 0.001). Cultures in both groups of patients were negative after 24-48 hours post-treatment. Clinical percentage of success was 100% for lomefloxacin and 96% for those treated with trimethoprim/sulfamethozazol. Mild reactions were reported in 3 and 4 patients of each group respectively.

AB - Fifty patients suffering acute bacterial diarrhea were studied under the design of single-blind randomly allocated and prospective. They received orally a single daily dose of 400 mg of lomefloxacin or trimethoprim/sulfamethoxazole 160/800 mg B.I.D. during five days. Evaluation was made in 47 patients: 23 corresponding to lomefloxacin group and 24 for the comparative preparate. Mean duration of diarrhea in the lomefloxacin group was 1.5 days vs 2.0 days in the other therapeutic group (P _ 0.001). Cultures in both groups of patients were negative after 24-48 hours post-treatment. Clinical percentage of success was 100% for lomefloxacin and 96% for those treated with trimethoprim/sulfamethozazol. Mild reactions were reported in 3 and 4 patients of each group respectively.

UR - https://www.scopus.com/pages/publications/0026402096

M3 - Artículo

AN - SCOPUS:0026402096

SN - 0185-1934

VL - 11

SP - 51

EP - 55

JO - Compendium de Investigaciones Clinicas Latinoamericanas

JF - Compendium de Investigaciones Clinicas Latinoamericanas

IS - 2

ER -

ESTUDIO COMPARATIVO: IOMEFLOXACINA VS. TRIMETOPRIM/SULFAMETOXAZOL EN EL TRATAMIENTO DE LA DIARREA AGUDA BACTERIANA DEL ADULTO

Abstract

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