Hemoglobin affinity and structure in high-altitude and sea-level carnivores from Peru

F. Leon-Velarde; C. De Muizon; J. A. Palacios; D. Clark; C. C. Monge

doi:10.1016/0300-9629(95)02083-7

Hemoglobin affinity and structure in high-altitude and sea-level carnivores from Peru

F. Leon-Velarde
, C. De Muizon
, J. A. Palacios
, D. Clark
, C. C. Monge

Graduate School

Universidad Peruana Cayetano Heredia

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

We compared hemoglobin affinity (P₅₀) and structure of high altitude (HA) carnivores with populations of the same species or genus living at sea level (SL). P₅₀ was measured in cats, pumas and foxes. It differed in animals occupying both niches. SL: cat 29.3 torr, puma 36.3 torr, fox 26.2 torr; HA: cat 22.5 torr, puma 3 1.1 torr, fox 18.5 torr. Heme and globins were fractionated by HPLC. Puma and fox hemoglobins also showed structural differences. P₅₀ is lower in genotypically HA-adapted species studied and can differentiate SL and HA populations of the same species.

Original language	English
Pages (from-to)	407-411
Number of pages	5
Journal	Comparative Biochemistry and Physiology -- Part A: Physiology
Volume	113
Issue number	4
DOIs	https://doi.org/10.1016/0300-9629(95)02083-7
State	Published - 1996

Keywords

Andean mammals
hemoglobin affinity
high-altitude adaptation
high-altitude carnivores

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title = "Hemoglobin affinity and structure in high-altitude and sea-level carnivores from Peru",

abstract = "We compared hemoglobin affinity (P50) and structure of high altitude (HA) carnivores with populations of the same species or genus living at sea level (SL). P50 was measured in cats, pumas and foxes. It differed in animals occupying both niches. SL: cat 29.3 torr, puma 36.3 torr, fox 26.2 torr; HA: cat 22.5 torr, puma 3 1.1 torr, fox 18.5 torr. Heme and globins were fractionated by HPLC. Puma and fox hemoglobins also showed structural differences. P50 is lower in genotypically HA-adapted species studied and can differentiate SL and HA populations of the same species.",

keywords = "Andean mammals, hemoglobin affinity, high-altitude adaptation, high-altitude carnivores",

author = "F. Leon-Velarde and \{De Muizon\}, C. and Palacios, \{J. A.\} and D. Clark and Monge, \{C. C.\}",

year = "1996",

doi = "10.1016/0300-9629(95)02083-7",

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volume = "113",

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journal = "Comparative Biochemistry and Physiology -- Part A: Physiology",

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TY - JOUR

T1 - Hemoglobin affinity and structure in high-altitude and sea-level carnivores from Peru

AU - Leon-Velarde, F.

AU - De Muizon, C.

AU - Palacios, J. A.

AU - Clark, D.

AU - Monge, C. C.

PY - 1996

Y1 - 1996

N2 - We compared hemoglobin affinity (P50) and structure of high altitude (HA) carnivores with populations of the same species or genus living at sea level (SL). P50 was measured in cats, pumas and foxes. It differed in animals occupying both niches. SL: cat 29.3 torr, puma 36.3 torr, fox 26.2 torr; HA: cat 22.5 torr, puma 3 1.1 torr, fox 18.5 torr. Heme and globins were fractionated by HPLC. Puma and fox hemoglobins also showed structural differences. P50 is lower in genotypically HA-adapted species studied and can differentiate SL and HA populations of the same species.

AB - We compared hemoglobin affinity (P50) and structure of high altitude (HA) carnivores with populations of the same species or genus living at sea level (SL). P50 was measured in cats, pumas and foxes. It differed in animals occupying both niches. SL: cat 29.3 torr, puma 36.3 torr, fox 26.2 torr; HA: cat 22.5 torr, puma 3 1.1 torr, fox 18.5 torr. Heme and globins were fractionated by HPLC. Puma and fox hemoglobins also showed structural differences. P50 is lower in genotypically HA-adapted species studied and can differentiate SL and HA populations of the same species.

KW - Andean mammals

KW - hemoglobin affinity

KW - high-altitude adaptation

KW - high-altitude carnivores

UR - https://www.scopus.com/pages/publications/0029898390

U2 - 10.1016/0300-9629(95)02083-7

DO - 10.1016/0300-9629(95)02083-7

M3 - Artículo

C2 - 8689525

AN - SCOPUS:0029898390

SN - 0300-9629

VL - 113

SP - 407

EP - 411

JO - Comparative Biochemistry and Physiology -- Part A: Physiology

JF - Comparative Biochemistry and Physiology -- Part A: Physiology

IS - 4

ER -

Hemoglobin affinity and structure in high-altitude and sea-level carnivores from Peru

Abstract

Keywords

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