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HLA studies in brucellar spondylitis

  • G. S. Alarcón
  • , E. Gotuzzo
  • , S. A. Hinostroza
  • , C. Carrillo
  • , T. S. Bocanegra
  • , L. R. Espinoza
  • Universidad Peruana Cayetano Heredia
  • University of South Florida, Tampa
  • University of Alabama at Birmingham

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Among the clinical manifestations of brucellosis, arthritis may occur in over one-third of the patients. Different articular syndromes have been well recognized: some are definitely infectious in nature, whereas others appear to be reactive. The possibility that B27 and B7-CREG antigens could predispose to the occurrence of brucellar spondylitis was investigated in 14 mestizo Peruvian patients. No association was found. Since there is a low frequency of B27 and B7-CREG in the control population, the possibility that a "native" antigen could be the predisposing one remains to be elucidated.

Original languageEnglish
Pages (from-to)312-314
Number of pages3
JournalClinical Rheumatology
Volume4
Issue number3
DOIs
StatePublished - Sep 1985

Keywords

  • Brucellosis
  • HLA Antigens
  • Infectious/Reactive Arthritis

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