Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1

Saul J. Santivañez; Ariana M. Gutierrez; Mara C. Rosenzvit; Patricia M. Muzulin; Mary L. Rodriguez; Julio C. Vasquez; Silvia Rodriguez; Armando E. Gonzalez; Robert H. Gilman; Hector H. Garcia

doi:10.4269/ajtmh.2008.79.89

Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1

Saul J. Santivañez
, Ariana M. Gutierrez
, Mara C. Rosenzvit
, Patricia M. Muzulin
, Mary L. Rodriguez
, Julio C. Vasquez
, Silvia Rodriguez
, Armando E. Gonzalez
, Robert H. Gilman
, Hector H. Garcia

School of Science and Engineering

Universidad Peruana Cayetano Heredia
Instituto Nacional de Enfermedades Infecciosas
Instituto Nacional de Ciencias Neurológicas
Hospital Nacional Dos de Mayo
Univ. Nacional Mayor de San Marcos
Johns Hopkins Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95%) belonged to the common sheep strain (G1). The remaining samples belonged to the camel strain (G6). The G1 genotype was most frequently found in human cases of cystic hydatid disease (CHD) in Peru. Local control measures should focus primarily on decreasing dog and sheep infection rather than intermediate reservoirs.

Original language	English
Pages (from-to)	89-92
Number of pages	4
Journal	American Journal of Tropical Medicine and Hygiene
Volume	79
Issue number	1
DOIs	https://doi.org/10.4269/ajtmh.2008.79.89
State	Published - Jul 2008

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Santivañez, S. J., Gutierrez, A. M., Rosenzvit, M. C., Muzulin, P. M., Rodriguez, M. L., Vasquez, J. C., Rodriguez, S., Gonzalez, A. E., Gilman, R. H., & Garcia, H. H. (2008). Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1. American Journal of Tropical Medicine and Hygiene, 79(1), 89-92. https://doi.org/10.4269/ajtmh.2008.79.89

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title = "Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1",

abstract = "A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95\%) belonged to the common sheep strain (G1). The remaining samples belonged to the camel strain (G6). The G1 genotype was most frequently found in human cases of cystic hydatid disease (CHD) in Peru. Local control measures should focus primarily on decreasing dog and sheep infection rather than intermediate reservoirs.",

author = "Santiva{\~n}ez, \{Saul J.\} and Gutierrez, \{Ariana M.\} and Rosenzvit, \{Mara C.\} and Muzulin, \{Patricia M.\} and Rodriguez, \{Mary L.\} and Vasquez, \{Julio C.\} and Silvia Rodriguez and Gonzalez, \{Armando E.\} and Gilman, \{Robert H.\} and Garcia, \{Hector H.\}",

year = "2008",

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doi = "10.4269/ajtmh.2008.79.89",

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AU - Rosenzvit, Mara C.

AU - Muzulin, Patricia M.

AU - Rodriguez, Mary L.

AU - Vasquez, Julio C.

AU - Rodriguez, Silvia

AU - Gonzalez, Armando E.

AU - Gilman, Robert H.

AU - Garcia, Hector H.

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AB - A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95%) belonged to the common sheep strain (G1). The remaining samples belonged to the camel strain (G6). The G1 genotype was most frequently found in human cases of cystic hydatid disease (CHD) in Peru. Local control measures should focus primarily on decreasing dog and sheep infection rather than intermediate reservoirs.

UR - https://www.scopus.com/pages/publications/46849110614

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AN - SCOPUS:46849110614

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JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

IS - 1

ER -

Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1

Abstract

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