Intermediate susceptibility to ciprofloxacin among Salmonella enterica serovar Typhi isolates in Lima, Peru

Coralith García; Veerle Lejon; Gertrudis Horna; Lizeth Astocondor; Raymond Vanhoof; Sophie Bertrand; Jan Jacobs

doi:10.1128/JCM.02663-13

Intermediate susceptibility to ciprofloxacin among Salmonella enterica serovar Typhi isolates in Lima, Peru

Coralith García
, Veerle Lejon
, Gertrudis Horna
, Lizeth Astocondor
, Raymond Vanhoof
, Sophie Bertrand
, Jan Jacobs

Institut de Recherche Pour le Développement, UMR177 IRD/CIR AD INTERTRYP
Institute of Tropical Medicine
Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt
Scientific Institute of Public Health, Brussels

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Thirty-three Salmonella enterica serovar Typhi blood isolates from Lima, Peru (2008 to 2012), were fully susceptible to trim-ethoprim-sulfamethoxazole, chloramphenicol, ceftriaxone, and tetracycline; 8/33 (24.2%) showed intermediate susceptibility to ciprofloxacin carrying mutations in the quinolone resistance-determining region of the gyrA gene (Ser83-Phe and Asp87-Asn) and in the gyrB gene (Ser464-Phe).

Original language	English
Pages (from-to)	968-970
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	52
Issue number	3
DOIs	https://doi.org/10.1128/JCM.02663-13
State	Published - Mar 2014

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abstract = "Thirty-three Salmonella enterica serovar Typhi blood isolates from Lima, Peru (2008 to 2012), were fully susceptible to trim-ethoprim-sulfamethoxazole, chloramphenicol, ceftriaxone, and tetracycline; 8/33 (24.2\%) showed intermediate susceptibility to ciprofloxacin carrying mutations in the quinolone resistance-determining region of the gyrA gene (Ser83-Phe and Asp87-Asn) and in the gyrB gene (Ser464-Phe).",

author = "Coralith Garc{\'i}a and Veerle Lejon and Gertrudis Horna and Lizeth Astocondor and Raymond Vanhoof and Sophie Bertrand and Jan Jacobs",

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T1 - Intermediate susceptibility to ciprofloxacin among Salmonella enterica serovar Typhi isolates in Lima, Peru

AU - García, Coralith

AU - Lejon, Veerle

AU - Horna, Gertrudis

AU - Astocondor, Lizeth

AU - Vanhoof, Raymond

AU - Bertrand, Sophie

AU - Jacobs, Jan

PY - 2014/3

Y1 - 2014/3

N2 - Thirty-three Salmonella enterica serovar Typhi blood isolates from Lima, Peru (2008 to 2012), were fully susceptible to trim-ethoprim-sulfamethoxazole, chloramphenicol, ceftriaxone, and tetracycline; 8/33 (24.2%) showed intermediate susceptibility to ciprofloxacin carrying mutations in the quinolone resistance-determining region of the gyrA gene (Ser83-Phe and Asp87-Asn) and in the gyrB gene (Ser464-Phe).

AB - Thirty-three Salmonella enterica serovar Typhi blood isolates from Lima, Peru (2008 to 2012), were fully susceptible to trim-ethoprim-sulfamethoxazole, chloramphenicol, ceftriaxone, and tetracycline; 8/33 (24.2%) showed intermediate susceptibility to ciprofloxacin carrying mutations in the quinolone resistance-determining region of the gyrA gene (Ser83-Phe and Asp87-Asn) and in the gyrB gene (Ser464-Phe).

UR - https://www.scopus.com/pages/publications/84894532130

U2 - 10.1128/JCM.02663-13

DO - 10.1128/JCM.02663-13

M3 - Artículo

C2 - 24371234

AN - SCOPUS:84894532130

SN - 0095-1137

VL - 52

SP - 968

EP - 970

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

IS - 3

ER -

Intermediate susceptibility to ciprofloxacin among Salmonella enterica serovar Typhi isolates in Lima, Peru

Abstract

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