TY - JOUR
T1 - Isolation of leishmanicidal triterpenes and lignans from the amazonian liana Doliocarpus dentatus (Dilleniaceae)
AU - Sauvain, Michel
AU - Kunesch, Nicole
AU - Poisson, Jacques
AU - Gantier, Jean Charles
AU - Gayral, Philippe
AU - Dedet, Jean Pierre
PY - 1996/2
Y1 - 1996/2
N2 - The in vitro antileishmanial activity of triterpenes and lignans of an Amazonian medicinal plant, Doliocarpus dentatus (Aublet) Standley, is reported for the first time against amastigotes of Leishmania amazonensis. Terpenes, for example, betulinic acid, betulin and betulinaldehyde were isolated by bioassay-linked extraction. The lignans were characterized as (+) pinoresinol, (+) medioresinol and (-) lirioresinol B.
AB - The in vitro antileishmanial activity of triterpenes and lignans of an Amazonian medicinal plant, Doliocarpus dentatus (Aublet) Standley, is reported for the first time against amastigotes of Leishmania amazonensis. Terpenes, for example, betulinic acid, betulin and betulinaldehyde were isolated by bioassay-linked extraction. The lignans were characterized as (+) pinoresinol, (+) medioresinol and (-) lirioresinol B.
KW - (+) Medioresinol
KW - (-) Lirioresinol B
KW - Betulin aldehyde
KW - Doliocarpus detatus
KW - Leishmanicidal activity
UR - https://www.scopus.com/pages/publications/0030063335
U2 - 10.1002/(SICI)1099-1573(199602)10:1<1::AID-PTR757>3.0.CO;2-A
DO - 10.1002/(SICI)1099-1573(199602)10:1<1::AID-PTR757>3.0.CO;2-A
M3 - Artículo
AN - SCOPUS:0030063335
SN - 0951-418X
VL - 10
SP - 1
EP - 4
JO - Phytotherapy Research
JF - Phytotherapy Research
IS - 1
ER -