Larvicidal, antimycobacterial and antifungal compounds from the bark of the peruvian plant Swartzia polyphylla DC

Rosario Rojas; Betty Bustamante; Palmira Ventosilla; Irma Fernádez; Luz Caviedes; Robert Henry Gilman; Olga Lock; Gerald Bruce Hammond

doi:10.1248/cpb.54

Larvicidal, antimycobacterial and antifungal compounds from the bark of the peruvian plant Swartzia polyphylla DC

Rosario Rojas
, Betty Bustamante
, Palmira Ventosilla
, Irma Fernádez
, Luz Caviedes
, Robert Henry Gilman
, Olga Lock
, Gerald Bruce Hammond

Unidad de Micología Clínica

Universidad Peruana Cayetano Heredia
Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt
Johns Hopkins Bloomberg School of Public Health
Pontificia Universidad Católica del Perú
University of Louisville

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

The 95% ethanol extract of the bark of Swartzia polyphylla DC (Fabaceae) possesses important larvicidal, antimycobacterial and antifungal activity in vitro. Bioassay-guided studies performed on the crude ethanol extract afforded T-cadinol as the larvicidal and anti-Mycobacterium tuberculosis principle, while the antifungal activity of the extract is due to the presence of the flavonoids biochanin A and dihydrobiochanin A.

Original language	English
Pages (from-to)	278-279
Number of pages	2
Journal	Chemical and Pharmaceutical Bulletin
Volume	54
Issue number	2
DOIs	https://doi.org/10.1248/cpb.54
State	Published - 1 Feb 2006

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Antifungal
Antimycobacterial
Biochanin A
Dihydrobiochanin A
Larvicidal
Swartzia polyphylla

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10.1248/cpb.54

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title = "Larvicidal, antimycobacterial and antifungal compounds from the bark of the peruvian plant Swartzia polyphylla DC",

abstract = "The 95\% ethanol extract of the bark of Swartzia polyphylla DC (Fabaceae) possesses important larvicidal, antimycobacterial and antifungal activity in vitro. Bioassay-guided studies performed on the crude ethanol extract afforded T-cadinol as the larvicidal and anti-Mycobacterium tuberculosis principle, while the antifungal activity of the extract is due to the presence of the flavonoids biochanin A and dihydrobiochanin A.",

keywords = "Antifungal, Antimycobacterial, Biochanin A, Dihydrobiochanin A, Larvicidal, Swartzia polyphylla",

author = "Rosario Rojas and Betty Bustamante and Palmira Ventosilla and Irma Fern{\'a}dez and Luz Caviedes and Gilman, \{Robert Henry\} and Olga Lock and Hammond, \{Gerald Bruce\}",

year = "2006",

month = feb,

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doi = "10.1248/cpb.54",

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volume = "54",

pages = "278--279",

journal = "Chemical and Pharmaceutical Bulletin",

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T1 - Larvicidal, antimycobacterial and antifungal compounds from the bark of the peruvian plant Swartzia polyphylla DC

AU - Rojas, Rosario

AU - Bustamante, Betty

AU - Ventosilla, Palmira

AU - Fernádez, Irma

AU - Caviedes, Luz

AU - Gilman, Robert Henry

AU - Lock, Olga

AU - Hammond, Gerald Bruce

PY - 2006/2/1

Y1 - 2006/2/1

N2 - The 95% ethanol extract of the bark of Swartzia polyphylla DC (Fabaceae) possesses important larvicidal, antimycobacterial and antifungal activity in vitro. Bioassay-guided studies performed on the crude ethanol extract afforded T-cadinol as the larvicidal and anti-Mycobacterium tuberculosis principle, while the antifungal activity of the extract is due to the presence of the flavonoids biochanin A and dihydrobiochanin A.

AB - The 95% ethanol extract of the bark of Swartzia polyphylla DC (Fabaceae) possesses important larvicidal, antimycobacterial and antifungal activity in vitro. Bioassay-guided studies performed on the crude ethanol extract afforded T-cadinol as the larvicidal and anti-Mycobacterium tuberculosis principle, while the antifungal activity of the extract is due to the presence of the flavonoids biochanin A and dihydrobiochanin A.

KW - Antifungal

KW - Antimycobacterial

KW - Biochanin A

KW - Dihydrobiochanin A

KW - Larvicidal

KW - Swartzia polyphylla

UR - https://www.scopus.com/pages/publications/32044456744

U2 - 10.1248/cpb.54

DO - 10.1248/cpb.54

M3 - Artículo

C2 - 16462085

AN - SCOPUS:32044456744

SN - 0009-2363

VL - 54

SP - 278

EP - 279

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 2

ER -

Larvicidal, antimycobacterial and antifungal compounds from the bark of the peruvian plant Swartzia polyphylla DC

Abstract

UN SDGs

Keywords

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