Liquid chromatographic analysis of cocaine and benzoylecgonine in plasma of traditional coca chewers from Bolivia during exercise

C. Rerat; M. Sauvain; P. P. Rop; E. Ruiz; M. Bresson; A. Viala

doi:10.1016/S0378-8741(97)00029-9

Liquid chromatographic analysis of cocaine and benzoylecgonine in plasma of traditional coca chewers from Bolivia during exercise

C. Rerat
, M. Sauvain
, P. P. Rop
, E. Ruiz
, M. Bresson
, A. Viala

Universidad Nacional Mayor de San Andrés
Inst. Francais Rech. Sci. D.
Laboratoire de Police Scientifique

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The purpose of the present study was to determine the amount of cocaine and benzoylecgonine in the plasma of Aymara Indians from the Bolivian Andes after traditional chewing of coca leaves during exercise performance. The determination was carried out by high performance liquid chromatography after solid-liquid extraction. The results showed that such use of coca leaves is well correlated with pharmacologically active concentration of cocaine in plasma.

Original language	English
Pages (from-to)	173-178
Number of pages	6
Journal	Journal of Ethnopharmacology
Volume	56
Issue number	3
DOIs	https://doi.org/10.1016/S0378-8741(97)00029-9
State	Published - May 1997
Externally published	Yes

Keywords

Aymara Indians
Benzoylecgonine
Coca chewing
Cocaine
HPLC
Plasma concentrations

Access to Document

10.1016/S0378-8741(97)00029-9

Cite this

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title = "Liquid chromatographic analysis of cocaine and benzoylecgonine in plasma of traditional coca chewers from Bolivia during exercise",

abstract = "The purpose of the present study was to determine the amount of cocaine and benzoylecgonine in the plasma of Aymara Indians from the Bolivian Andes after traditional chewing of coca leaves during exercise performance. The determination was carried out by high performance liquid chromatography after solid-liquid extraction. The results showed that such use of coca leaves is well correlated with pharmacologically active concentration of cocaine in plasma.",

keywords = "Aymara Indians, Benzoylecgonine, Coca chewing, Cocaine, HPLC, Plasma concentrations",

author = "C. Rerat and M. Sauvain and Rop, \{P. P.\} and E. Ruiz and M. Bresson and A. Viala",

year = "1997",

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doi = "10.1016/S0378-8741(97)00029-9",

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T1 - Liquid chromatographic analysis of cocaine and benzoylecgonine in plasma of traditional coca chewers from Bolivia during exercise

AU - Rerat, C.

AU - Sauvain, M.

AU - Rop, P. P.

AU - Ruiz, E.

AU - Bresson, M.

AU - Viala, A.

PY - 1997/5

Y1 - 1997/5

N2 - The purpose of the present study was to determine the amount of cocaine and benzoylecgonine in the plasma of Aymara Indians from the Bolivian Andes after traditional chewing of coca leaves during exercise performance. The determination was carried out by high performance liquid chromatography after solid-liquid extraction. The results showed that such use of coca leaves is well correlated with pharmacologically active concentration of cocaine in plasma.

AB - The purpose of the present study was to determine the amount of cocaine and benzoylecgonine in the plasma of Aymara Indians from the Bolivian Andes after traditional chewing of coca leaves during exercise performance. The determination was carried out by high performance liquid chromatography after solid-liquid extraction. The results showed that such use of coca leaves is well correlated with pharmacologically active concentration of cocaine in plasma.

KW - Aymara Indians

KW - Benzoylecgonine

KW - Coca chewing

KW - Cocaine

KW - HPLC

KW - Plasma concentrations

UR - https://www.scopus.com/pages/publications/0030980934

U2 - 10.1016/S0378-8741(97)00029-9

DO - 10.1016/S0378-8741(97)00029-9

M3 - Artículo

C2 - 9201606

AN - SCOPUS:0030980934

SN - 0378-8741

VL - 56

SP - 173

EP - 178

JO - Journal of Ethnopharmacology

JF - Journal of Ethnopharmacology

IS - 3

ER -

Liquid chromatographic analysis of cocaine and benzoylecgonine in plasma of traditional coca chewers from Bolivia during exercise

Abstract

Keywords

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