Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America

Raquel B. De Boni; Bryan E. Shepherd; Beatriz Grinsztejn; Carina Cesar; Claudia Cortés; Denis Padgett; Eduardo Gotuzzo; Pablo F. Belaunzarán-Zamudio; Peter F. Rebeiro; Stephany N. Duda; Catherine C. McGowan

doi:10.1007/s10461-016-1398-6

Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America

Raquel B. De Boni
, Bryan E. Shepherd
, Beatriz Grinsztejn
, Carina Cesar
, Claudia Cortés
, Denis Padgett
, Eduardo Gotuzzo
, Pablo F. Belaunzarán-Zamudio
, Peter F. Rebeiro
, Stephany N. Duda
, Catherine C. McGowan

Instituto Nacional de Infectologia Evandro Chagas (INI)
Vanderbilt University
Fundación Huesped
Fundación Arriarán
Universidad Peruana Cayetano Heredia
Instituto Hondureno de Seguridad Social and Hospital Escuela
Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

This cross-sectional study describes substance use prevalence and its association with combination antiretroviral therapy (cART) adherence among 3343 individuals receiving care at HIV clinics in Argentina, Brazil, Chile, Honduras, Mexico, and Peru. A rapid screening tool evaluated self-reported 7-day recall of alcohol, marijuana, cocaine, heroin, and methamphetamine use, and missed cART doses. Overall, 29.3 % individuals reported having ≥1 alcoholic drinks, 5.0 % reported any illicit drug use and 17.0 % reported missed cART doses. In the logistic regression model, compared to no substance use, alcohol use [adjusted odds ratio (AOR) = 2.46, 95 % confidence interval (CI): 1.99–3.05], illicit drug use (AOR = 3.57, 95 % CI: 2.02–6.30), and using both alcohol and illicit drugs (AOR = 4.98, 95 % CI: 3.19–7.79) were associated with missed cART doses. The associations between substance use and likelihood of missing cART doses point to the need of targeting alcohol and illicit drug use to improve adherence among people living with HIV in Latin America.

Original language	English
Pages (from-to)	2692-2699
Number of pages	8
Journal	AIDS and behavior
Volume	20
Issue number	11
DOIs	https://doi.org/10.1007/s10461-016-1398-6
State	Published - 1 Nov 2016
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Adherence
HIV/AIDS
Latin America
Substance use

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10.1007/s10461-016-1398-6

Cite this

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title = "Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America",

abstract = "This cross-sectional study describes substance use prevalence and its association with combination antiretroviral therapy (cART) adherence among 3343 individuals receiving care at HIV clinics in Argentina, Brazil, Chile, Honduras, Mexico, and Peru. A rapid screening tool evaluated self-reported 7-day recall of alcohol, marijuana, cocaine, heroin, and methamphetamine use, and missed cART doses. Overall, 29.3 \% individuals reported having ≥1 alcoholic drinks, 5.0 \% reported any illicit drug use and 17.0 \% reported missed cART doses. In the logistic regression model, compared to no substance use, alcohol use [adjusted odds ratio (AOR) = 2.46, 95 \% confidence interval (CI): 1.99–3.05], illicit drug use (AOR = 3.57, 95 \% CI: 2.02–6.30), and using both alcohol and illicit drugs (AOR = 4.98, 95 \% CI: 3.19–7.79) were associated with missed cART doses. The associations between substance use and likelihood of missing cART doses point to the need of targeting alcohol and illicit drug use to improve adherence among people living with HIV in Latin America.",

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AU - Cesar, Carina

AU - Cortés, Claudia

AU - Padgett, Denis

AU - Gotuzzo, Eduardo

AU - Belaunzarán-Zamudio, Pablo F.

AU - Rebeiro, Peter F.

AU - Duda, Stephany N.

AU - McGowan, Catherine C.

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N2 - This cross-sectional study describes substance use prevalence and its association with combination antiretroviral therapy (cART) adherence among 3343 individuals receiving care at HIV clinics in Argentina, Brazil, Chile, Honduras, Mexico, and Peru. A rapid screening tool evaluated self-reported 7-day recall of alcohol, marijuana, cocaine, heroin, and methamphetamine use, and missed cART doses. Overall, 29.3 % individuals reported having ≥1 alcoholic drinks, 5.0 % reported any illicit drug use and 17.0 % reported missed cART doses. In the logistic regression model, compared to no substance use, alcohol use [adjusted odds ratio (AOR) = 2.46, 95 % confidence interval (CI): 1.99–3.05], illicit drug use (AOR = 3.57, 95 % CI: 2.02–6.30), and using both alcohol and illicit drugs (AOR = 4.98, 95 % CI: 3.19–7.79) were associated with missed cART doses. The associations between substance use and likelihood of missing cART doses point to the need of targeting alcohol and illicit drug use to improve adherence among people living with HIV in Latin America.

AB - This cross-sectional study describes substance use prevalence and its association with combination antiretroviral therapy (cART) adherence among 3343 individuals receiving care at HIV clinics in Argentina, Brazil, Chile, Honduras, Mexico, and Peru. A rapid screening tool evaluated self-reported 7-day recall of alcohol, marijuana, cocaine, heroin, and methamphetamine use, and missed cART doses. Overall, 29.3 % individuals reported having ≥1 alcoholic drinks, 5.0 % reported any illicit drug use and 17.0 % reported missed cART doses. In the logistic regression model, compared to no substance use, alcohol use [adjusted odds ratio (AOR) = 2.46, 95 % confidence interval (CI): 1.99–3.05], illicit drug use (AOR = 3.57, 95 % CI: 2.02–6.30), and using both alcohol and illicit drugs (AOR = 4.98, 95 % CI: 3.19–7.79) were associated with missed cART doses. The associations between substance use and likelihood of missing cART doses point to the need of targeting alcohol and illicit drug use to improve adherence among people living with HIV in Latin America.

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KW - HIV/AIDS

KW - Latin America

KW - Substance use

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ER -

Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America

Abstract

UN SDGs

Keywords

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