TY - JOUR
T1 - Taenia solium neurocysticercosis
T2 - lts current epidemiological, diagnostic, therapeutic, and control landscapes
AU - Bustos, Javier A.
AU - Coyle, Christina M.
AU - Thakur, Kiran T.
AU - Guzman, Carolina
AU - Toribio, Luz M.
AU - Arroyo, Gianfranco
AU - Saavedra, Herbert
AU - Mwape, Kabemba E.
AU - Rajshekhar, Vedantam
AU - Garcia, Hector H.
AU - the Cysticercosis Working Group in Peru (cwgp), Cysticercosis Working Group in Peru (cwgp)
N1 - Publisher Copyright:
© 2026 Bustos et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2026/2
Y1 - 2026/2
N2 - Neurocysticercosis is the most common helminthic parasitic disease affecting the human central nervous system and is pleomorphic in its presentation. It is frequently encountered in daily practice in most parts of the world, and also commonly seen in industrialized countries in immigrant populations. In the past decade, new treatment (combined anti-parasitic drugs, increased attention to reducing treatment-associated inflammation and damage, new surgical strategies), and diagnostic (more specific antigen and antibody detection concepts and tools, more sensitive magnetic resonance imaging sequences) approaches, new animal models, and data on control of transmission have emerged. Still, diagnostic challenges persist and treatment approaches for some types of disease may differ, affecting clinical practice. This review provides clinicians in endemic and non-endemic countries with a comprehensive and practical reference to understand the variabilities in clinical expression of the disease and the optimal diagnostic and treatment approaches.
AB - Neurocysticercosis is the most common helminthic parasitic disease affecting the human central nervous system and is pleomorphic in its presentation. It is frequently encountered in daily practice in most parts of the world, and also commonly seen in industrialized countries in immigrant populations. In the past decade, new treatment (combined anti-parasitic drugs, increased attention to reducing treatment-associated inflammation and damage, new surgical strategies), and diagnostic (more specific antigen and antibody detection concepts and tools, more sensitive magnetic resonance imaging sequences) approaches, new animal models, and data on control of transmission have emerged. Still, diagnostic challenges persist and treatment approaches for some types of disease may differ, affecting clinical practice. This review provides clinicians in endemic and non-endemic countries with a comprehensive and practical reference to understand the variabilities in clinical expression of the disease and the optimal diagnostic and treatment approaches.
UR - https://www.scopus.com/pages/publications/105031190645
U2 - 10.1371/journal.pntd.0013937
DO - 10.1371/journal.pntd.0013937
M3 - Artículo
C2 - 41734210
AN - SCOPUS:105031190645
SN - 1935-2727
VL - 20
JO - PLoS Neglected Tropical Diseases
JF - PLoS Neglected Tropical Diseases
IS - 2
M1 - e0013937
ER -