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The greatest steps towards the discovery of Vibrio cholerae

  • University of Florence

Research output: Contribution to journalReview articlepeer-review

58 Scopus citations

Abstract

In the 19th century, there was extensive research on cholera: the disease was generally attributed to miasmatic causes, but this concept was replaced, between about 1850 and 1910, by the scientifically founded germ theory of disease. In 1883, Robert Koch identified the vibrion for the second time, after Filippo Pacini's discovery in 1854: Koch isolated the comma bacillus in pure culture and explained its mode of transmission, solving an enigma that had lasted for centuries. The aim of this article is to reconstruct the different steps towards the explanation of cholera, paying particular attention to the events occurring in the pivotal year 1854.

Original languageEnglish
Pages (from-to)191-195
Number of pages5
JournalClinical Microbiology and Infection
Volume20
Issue number3
DOIs
StatePublished - Mar 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Filippo Pacini
  • History of cholera
  • John Snow
  • Robert Koch
  • Vibrion

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