Time to initiation of multidrug-resistant tuberculosis treatment and its relation with outcome in a high incidence district in Lima, Peru

L. Otero; A. De Orbegoso; A. F. Navarro; J. Ríos; T. Párraga; E. Gotuzzo; C. Seas; P. Van der Stuyft

doi:10.1111/tmi.12430

Time to initiation of multidrug-resistant tuberculosis treatment and its relation with outcome in a high incidence district in Lima, Peru

L. Otero
, A. De Orbegoso
, A. F. Navarro
, J. Ríos
, T. Párraga
, E. Gotuzzo
, C. Seas
, P. Van der Stuyft

Institute of Tropical Medicine
Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt
Ministerio de Salud
Ghent University

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Objective: To determine the time from diagnosis to start of multidrug resistant tuberculosis (MDR TB) treatment in Lima, Peru. Methods: We studied new smear-positive TB adults that were started on MDR TB treatment or that were switched to it between June 2008 and December 2011. Results: Time from the first positive smear to MDR-TB treatment was >30 days in 35% (13/37) of patients. Among the 27% (24/88) of patients that switched to MDR-TB treatment, time from the last dose of a drug-susceptible regimen was >30 days. Conclusion: Start of and switching to MDR TB treatment is still delayed.

Original language	English
Pages (from-to)	322-325
Number of pages	4
Journal	Tropical Medicine and International Health
Volume	20
Issue number	3
DOIs	https://doi.org/10.1111/tmi.12430
State	Published - 1 Mar 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Multidrug resistant
Peru
Time to treatment
Tuberculosis

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10.1111/tmi.12430

Cite this

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title = "Time to initiation of multidrug-resistant tuberculosis treatment and its relation with outcome in a high incidence district in Lima, Peru",

abstract = "Objective: To determine the time from diagnosis to start of multidrug resistant tuberculosis (MDR TB) treatment in Lima, Peru. Methods: We studied new smear-positive TB adults that were started on MDR TB treatment or that were switched to it between June 2008 and December 2011. Results: Time from the first positive smear to MDR-TB treatment was >30 days in 35\% (13/37) of patients. Among the 27\% (24/88) of patients that switched to MDR-TB treatment, time from the last dose of a drug-susceptible regimen was >30 days. Conclusion: Start of and switching to MDR TB treatment is still delayed.",

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doi = "10.1111/tmi.12430",

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TY - JOUR

T1 - Time to initiation of multidrug-resistant tuberculosis treatment and its relation with outcome in a high incidence district in Lima, Peru

AU - Otero, L.

AU - De Orbegoso, A.

AU - Navarro, A. F.

AU - Ríos, J.

AU - Párraga, T.

AU - Gotuzzo, E.

AU - Seas, C.

AU - Van der Stuyft, P.

PY - 2015/3/1

Y1 - 2015/3/1

N2 - Objective: To determine the time from diagnosis to start of multidrug resistant tuberculosis (MDR TB) treatment in Lima, Peru. Methods: We studied new smear-positive TB adults that were started on MDR TB treatment or that were switched to it between June 2008 and December 2011. Results: Time from the first positive smear to MDR-TB treatment was >30 days in 35% (13/37) of patients. Among the 27% (24/88) of patients that switched to MDR-TB treatment, time from the last dose of a drug-susceptible regimen was >30 days. Conclusion: Start of and switching to MDR TB treatment is still delayed.

AB - Objective: To determine the time from diagnosis to start of multidrug resistant tuberculosis (MDR TB) treatment in Lima, Peru. Methods: We studied new smear-positive TB adults that were started on MDR TB treatment or that were switched to it between June 2008 and December 2011. Results: Time from the first positive smear to MDR-TB treatment was >30 days in 35% (13/37) of patients. Among the 27% (24/88) of patients that switched to MDR-TB treatment, time from the last dose of a drug-susceptible regimen was >30 days. Conclusion: Start of and switching to MDR TB treatment is still delayed.

KW - Multidrug resistant

KW - Peru

KW - Time to treatment

KW - Tuberculosis

UR - https://www.scopus.com/pages/publications/84922637897

U2 - 10.1111/tmi.12430

DO - 10.1111/tmi.12430

M3 - Artículo

C2 - 25429916

AN - SCOPUS:84922637897

SN - 1360-2276

VL - 20

SP - 322

EP - 325

JO - Tropical Medicine and International Health

JF - Tropical Medicine and International Health

IS - 3

ER -

Time to initiation of multidrug-resistant tuberculosis treatment and its relation with outcome in a high incidence district in Lima, Peru

Abstract

UN SDGs

Keywords

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