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Treponema pallidum pallidum genotypes and macrolide resistance status in syphilitic lesions among patients at 2 sexually transmitted infection clinics in Lima, Peru

  • Juan Antonio Flores
  • , Silver Keith Vargas
  • , Segundo Ramos Leon
  • , Danny Giancarlo Perez
  • , Lourdes Beatriz Ramos
  • , Jeremy Chow
  • , Kelika Anne Konda
  • , Gino Mauricio Calvo
  • , Hector J. Salvatierra
  • , Jeffrey D. Klaussner
  • , Carlos Fernando Caceres
  • Universidad Peruana Cayetano Heredia
  • University of California
  • Alberto Barton Clinic

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

We report the circulating genotypes and the frequency of macrolide-resistance patterns among Treponema pallidum pallidum DNA isolated from syphilitic lesions from patients who attended 2 sexual health clinics in Lima, Peru.We implemented and used amolecular typing scheme to describe local T. pallidum pallidum strains. Among 14 specimens, subtype 14d/f was the most prevalent strain in 7 fully typed T. pallidum DNA specimens obtained from men who have sex with men and transgender women presenting with chancre-like lesions. No macrolide-resistance mutations were found in T. pallidum DNA from 10 lesions.

Original languageEnglish
Pages (from-to)465-466
Number of pages2
JournalSexually Transmitted Diseases
Volume43
Issue number7
DOIs
StatePublished - 21 Jun 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being
  2. SDG 5 - Gender Equality
    SDG 5 Gender Equality

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