Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality

Jaime Soria; Alfredo Chiappe; Jorge Gallardo; Joseph R. Zunt; Andres G. Lescano

doi:10.1093/ofid/ofab345

Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality

Jaime Soria
, Alfredo Chiappe
, Jorge Gallardo
, Joseph R. Zunt
, Andres G. Lescano

School of Public Health and Administration

University of Kentucky
University of Washington
Hospital Nacional Dos de Mayo
School of Public Health

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

We conducted a retrospective cross-sectional study of adult hospitalized patients with confirmed tuberculous meningitis to determine the impact of the timing of treatment initiation on mortality. The mortality of tuberculous meningitis patients was high and was associated with delay in initiation of treatment, older age, HIV infection, and higher disease severity at admission.

Original language	English
Article number	ofab345
Journal	Open Forum Infectious Diseases
Volume	8
Issue number	7
DOIs	https://doi.org/10.1093/ofid/ofab345
State	Published - Jul 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

meningitis
mortality
tuberculosis

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10.1093/ofid/ofab345

Cite this

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title = "Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality",

abstract = "We conducted a retrospective cross-sectional study of adult hospitalized patients with confirmed tuberculous meningitis to determine the impact of the timing of treatment initiation on mortality. The mortality of tuberculous meningitis patients was high and was associated with delay in initiation of treatment, older age, HIV infection, and higher disease severity at admission.",

keywords = "meningitis, mortality, tuberculosis",

author = "Jaime Soria and Alfredo Chiappe and Jorge Gallardo and Zunt, \{Joseph R.\} and Lescano, \{Andres G.\}",

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year = "2021",

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T2 - Impact of Timing of Treatment Initiation on Mortality

AU - Soria, Jaime

AU - Chiappe, Alfredo

AU - Gallardo, Jorge

AU - Zunt, Joseph R.

AU - Lescano, Andres G.

PY - 2021/7

Y1 - 2021/7

N2 - We conducted a retrospective cross-sectional study of adult hospitalized patients with confirmed tuberculous meningitis to determine the impact of the timing of treatment initiation on mortality. The mortality of tuberculous meningitis patients was high and was associated with delay in initiation of treatment, older age, HIV infection, and higher disease severity at admission.

AB - We conducted a retrospective cross-sectional study of adult hospitalized patients with confirmed tuberculous meningitis to determine the impact of the timing of treatment initiation on mortality. The mortality of tuberculous meningitis patients was high and was associated with delay in initiation of treatment, older age, HIV infection, and higher disease severity at admission.

KW - meningitis

KW - mortality

KW - tuberculosis

UR - https://www.scopus.com/pages/publications/85112571349

U2 - 10.1093/ofid/ofab345

DO - 10.1093/ofid/ofab345

M3 - Artículo

AN - SCOPUS:85112571349

SN - 2328-8957

VL - 8

JO - Open Forum Infectious Diseases

JF - Open Forum Infectious Diseases

IS - 7

M1 - ofab345

ER -

Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality

Abstract

UN SDGs

Keywords

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