TY - JOUR
T1 - An outbreak of bartonella bacilliformis in an Endemic Andean community
AU - Clemente, Nuria Sanchez
AU - Ugarte-Gil, Cesar
AU - Solorzano, Nelson
AU - Maguiña, Ciro
AU - Moore, David
N1 - Publisher Copyright:
© 2016 Sanchez Clemente et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in anymedium, provided the original author and source are credited.
PY - 2016/3
Y1 - 2016/3
N2 - Background: Bartonellosis affects small Andean communities in Peru, Colombia and Ecuador. Research in this area has been limited. Methods: Retrospective review of 191 cases of bartonellosis managed in Caraz District Hospital, Peru, during the last outbreak (2003). Results: The majority of cases (65%) were 14 years old and younger. There was a peak in acute cases after the rainy season; chronic cases presented more constantly throughout the year. The sensitivity of blood smear against blood culture in acute disease was 25%. The most commonly used treatment for chronic disease was rifampicin; chloramphenicol was used to treat most acute cases. Complications arose in 6.8% and there were no deaths. Conclusions: Diagnostic and treatment algorithms for acute and chronic bartonellosis have been developed without a strong evidence base. Preparation of ready-to-go operational research protocols for future outbreaks would strengthen the evidence base for diagnostic and treatment strategies and enhance opportunities for control.
AB - Background: Bartonellosis affects small Andean communities in Peru, Colombia and Ecuador. Research in this area has been limited. Methods: Retrospective review of 191 cases of bartonellosis managed in Caraz District Hospital, Peru, during the last outbreak (2003). Results: The majority of cases (65%) were 14 years old and younger. There was a peak in acute cases after the rainy season; chronic cases presented more constantly throughout the year. The sensitivity of blood smear against blood culture in acute disease was 25%. The most commonly used treatment for chronic disease was rifampicin; chloramphenicol was used to treat most acute cases. Complications arose in 6.8% and there were no deaths. Conclusions: Diagnostic and treatment algorithms for acute and chronic bartonellosis have been developed without a strong evidence base. Preparation of ready-to-go operational research protocols for future outbreaks would strengthen the evidence base for diagnostic and treatment strategies and enhance opportunities for control.
UR - https://www.scopus.com/pages/publications/84962169608
U2 - 10.1371/journal.pone.0150525
DO - 10.1371/journal.pone.0150525
M3 - Artículo
C2 - 26991495
AN - SCOPUS:84962169608
SN - 1932-6203
VL - 11
JO - PLoS ONE
JF - PLoS ONE
IS - 3
M1 - e0150525
ER -