Evaluation of A PCR-Based Universal Heteroduplex Generator Assay As A Tool for Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis in Peru

Holger Mayta; Robert H. Gilman; Fanny Arenas; Teresa Valencia; Luz Caviedes; Sonia H. Montenegro; Eduardo Ticona; Jaime Ortiz; Rosa Chumpitaz; Carlton A. Evans; Diana L. Williams

doi:10.1128/JCM.41.12.5774-5777.2003

Evaluation of A PCR-Based Universal Heteroduplex Generator Assay As A Tool for Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis in Peru

Holger Mayta
, Robert H. Gilman
, Fanny Arenas
, Teresa Valencia
, Luz Caviedes
, Sonia H. Montenegro
, Eduardo Ticona
, Jaime Ortiz
, Rosa Chumpitaz
, Carlton A. Evans
, Diana L. Williams

Facultad de Ciencias e Ingeniería

Johns Hopkins Bloomberg School of Public Health
Universidad Peruana Cayetano Heredia
Asociación Benéfica PRISMA
Ochsner Medical Foundation
Hospital Nacional Dos de Mayo
Hospital María Auxiliadora
Imperial College London
U.S. Department of Health and Human Services

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17 Citas (Scopus)

Resumen

Multidrug-resistant tuberculosis is an increasing health problem worldwide, especially in developing countries. The PCR-UHG-Rif assay, which detects mutations within the rpoB gene associated with rifampin resistance, was evaluated for its ability and reliability to detect and identify drug-resistant Mycobacterium tuberculosis in a developing country where tuberculosis is highly endemic.

Idioma original	Inglés
Páginas (desde-hasta)	5774-5777
Número de páginas	4
Publicación	Journal of Clinical Microbiology
Volumen	41
N.º	12
DOI	https://doi.org/10.1128/JCM.41.12.5774-5777.2003
Estado	Publicada - dic. 2003

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Mayta, H., Gilman, R. H., Arenas, F., Valencia, T., Caviedes, L., Montenegro, S. H., Ticona, E., Ortiz, J., Chumpitaz, R., Evans, C. A., & Williams, D. L. (2003). Evaluation of A PCR-Based Universal Heteroduplex Generator Assay As A Tool for Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis in Peru. Journal of Clinical Microbiology, 41(12), 5774-5777. https://doi.org/10.1128/JCM.41.12.5774-5777.2003

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title = "Evaluation of A PCR-Based Universal Heteroduplex Generator Assay As A Tool for Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis in Peru",

abstract = "Multidrug-resistant tuberculosis is an increasing health problem worldwide, especially in developing countries. The PCR-UHG-Rif assay, which detects mutations within the rpoB gene associated with rifampin resistance, was evaluated for its ability and reliability to detect and identify drug-resistant Mycobacterium tuberculosis in a developing country where tuberculosis is highly endemic.",

author = "Holger Mayta and Gilman, \{Robert H.\} and Fanny Arenas and Teresa Valencia and Luz Caviedes and Montenegro, \{Sonia H.\} and Eduardo Ticona and Jaime Ortiz and Rosa Chumpitaz and Evans, \{Carlton A.\} and Williams, \{Diana L.\}",

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Mayta, H, Gilman, RH, Arenas, F, Valencia, T, Caviedes, L, Montenegro, SH, Ticona, E, Ortiz, J, Chumpitaz, R, Evans, CA & Williams, DL 2003, 'Evaluation of A PCR-Based Universal Heteroduplex Generator Assay As A Tool for Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis in Peru', Journal of Clinical Microbiology, vol. 41, n.º 12, pp. 5774-5777. https://doi.org/10.1128/JCM.41.12.5774-5777.2003

Evaluation of A PCR-Based Universal Heteroduplex Generator Assay As A Tool for Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis in Peru. / Mayta, Holger; Gilman, Robert H.; Arenas, Fanny et al.
En: Journal of Clinical Microbiology, Vol. 41, N.º 12, 12.2003, p. 5774-5777.

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

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AU - Mayta, Holger

AU - Gilman, Robert H.

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AU - Valencia, Teresa

AU - Caviedes, Luz

AU - Montenegro, Sonia H.

AU - Ticona, Eduardo

AU - Ortiz, Jaime

AU - Chumpitaz, Rosa

AU - Evans, Carlton A.

AU - Williams, Diana L.

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AB - Multidrug-resistant tuberculosis is an increasing health problem worldwide, especially in developing countries. The PCR-UHG-Rif assay, which detects mutations within the rpoB gene associated with rifampin resistance, was evaluated for its ability and reliability to detect and identify drug-resistant Mycobacterium tuberculosis in a developing country where tuberculosis is highly endemic.

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Evaluation of A PCR-Based Universal Heteroduplex Generator Assay As A Tool for Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis in Peru

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