Foxp3+ regulatory T cells in antiretroviral-naive HIV patients

Martin Montes; Dorothy E. Lewis; Cesar Sanchez; Diego Lopez De Castilla; Edward A. Graviss; Carlos Seas; Eduardo Gotuzzo; A. Clinton White

doi:10.1097/01.aids.0000238415.98194.38

Foxp3+ regulatory T cells in antiretroviral-naive HIV patients

Martin Montes
, Dorothy E. Lewis
, Cesar Sanchez
, Diego Lopez De Castilla
, Edward A. Graviss
, Carlos Seas
, Eduardo Gotuzzo
, A. Clinton White

Baylor College of Medicine
Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

56 Citas (Scopus)

Resumen

We characterized regulatory T cells from antiretroviral-naive HIV patients by flow cytometry. The proportion of CD4 cells positive for CD25 and Foxp3 was increased, mainly in those with CD4 cell counts less than 200 cells/μl. The total number of Foxp3-positive cells correlated with the CD4 cell count. Further studies are needed on whether Foxp3-positive cell numbers or function explain the susceptibility to autoimmune and inflammatory diseases seen in some patients with advanced HIV.

Idioma original	Inglés
Páginas (desde-hasta)	1669-1671
Número de páginas	3
Publicación	AIDS
Volumen	20
N.º	12
DOI	https://doi.org/10.1097/01.aids.0000238415.98194.38
Estado	Publicada - ago. 2006

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title = "Foxp3+ regulatory T cells in antiretroviral-naive HIV patients",

abstract = "We characterized regulatory T cells from antiretroviral-naive HIV patients by flow cytometry. The proportion of CD4 cells positive for CD25 and Foxp3 was increased, mainly in those with CD4 cell counts less than 200 cells/μl. The total number of Foxp3-positive cells correlated with the CD4 cell count. Further studies are needed on whether Foxp3-positive cell numbers or function explain the susceptibility to autoimmune and inflammatory diseases seen in some patients with advanced HIV.",

author = "Martin Montes and Lewis, \{Dorothy E.\} and Cesar Sanchez and \{De Castilla\}, \{Diego Lopez\} and Graviss, \{Edward A.\} and Carlos Seas and Eduardo Gotuzzo and White, \{A. Clinton\}",

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T1 - Foxp3+ regulatory T cells in antiretroviral-naive HIV patients

AU - Montes, Martin

AU - Lewis, Dorothy E.

AU - Sanchez, Cesar

AU - De Castilla, Diego Lopez

AU - Graviss, Edward A.

AU - Seas, Carlos

AU - Gotuzzo, Eduardo

AU - White, A. Clinton

PY - 2006/8

Y1 - 2006/8

N2 - We characterized regulatory T cells from antiretroviral-naive HIV patients by flow cytometry. The proportion of CD4 cells positive for CD25 and Foxp3 was increased, mainly in those with CD4 cell counts less than 200 cells/μl. The total number of Foxp3-positive cells correlated with the CD4 cell count. Further studies are needed on whether Foxp3-positive cell numbers or function explain the susceptibility to autoimmune and inflammatory diseases seen in some patients with advanced HIV.

AB - We characterized regulatory T cells from antiretroviral-naive HIV patients by flow cytometry. The proportion of CD4 cells positive for CD25 and Foxp3 was increased, mainly in those with CD4 cell counts less than 200 cells/μl. The total number of Foxp3-positive cells correlated with the CD4 cell count. Further studies are needed on whether Foxp3-positive cell numbers or function explain the susceptibility to autoimmune and inflammatory diseases seen in some patients with advanced HIV.

UR - https://www.scopus.com/pages/publications/33746675679

U2 - 10.1097/01.aids.0000238415.98194.38

DO - 10.1097/01.aids.0000238415.98194.38

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SN - 0269-9370

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SP - 1669

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JO - AIDS

JF - AIDS

IS - 12

ER -

Foxp3+ regulatory T cells in antiretroviral-naive HIV patients

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