Larvicidal, antimycobacterial and antifungal compounds from the bark of the peruvian plant Swartzia polyphylla DC

Rosario Rojas; Betty Bustamante; Palmira Ventosilla; Irma Fernádez; Luz Caviedes; Robert Henry Gilman; Olga Lock; Gerald Bruce Hammond

doi:10.1248/cpb.54

Larvicidal, antimycobacterial and antifungal compounds from the bark of the peruvian plant Swartzia polyphylla DC

Rosario Rojas
, Betty Bustamante
, Palmira Ventosilla
, Irma Fernádez
, Luz Caviedes
, Robert Henry Gilman
, Olga Lock
, Gerald Bruce Hammond

Unidad de Micología Clínica

Universidad Peruana Cayetano Heredia
Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt
Johns Hopkins Bloomberg School of Public Health
Pontificia Universidad Católica del Perú
University of Louisville

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32 Citas (Scopus)

Resumen

The 95% ethanol extract of the bark of Swartzia polyphylla DC (Fabaceae) possesses important larvicidal, antimycobacterial and antifungal activity in vitro. Bioassay-guided studies performed on the crude ethanol extract afforded T-cadinol as the larvicidal and anti-Mycobacterium tuberculosis principle, while the antifungal activity of the extract is due to the presence of the flavonoids biochanin A and dihydrobiochanin A.

Idioma original	Inglés
Páginas (desde-hasta)	278-279
Número de páginas	2
Publicación	Chemical and Pharmaceutical Bulletin
Volumen	54
N.º	2
DOI	https://doi.org/10.1248/cpb.54
Estado	Publicada - 1 feb. 2006

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title = "Larvicidal, antimycobacterial and antifungal compounds from the bark of the peruvian plant Swartzia polyphylla DC",

abstract = "The 95\% ethanol extract of the bark of Swartzia polyphylla DC (Fabaceae) possesses important larvicidal, antimycobacterial and antifungal activity in vitro. Bioassay-guided studies performed on the crude ethanol extract afforded T-cadinol as the larvicidal and anti-Mycobacterium tuberculosis principle, while the antifungal activity of the extract is due to the presence of the flavonoids biochanin A and dihydrobiochanin A.",

keywords = "Antifungal, Antimycobacterial, Biochanin A, Dihydrobiochanin A, Larvicidal, Swartzia polyphylla",

author = "Rosario Rojas and Betty Bustamante and Palmira Ventosilla and Irma Fern{\'a}dez and Luz Caviedes and Gilman, \{Robert Henry\} and Olga Lock and Hammond, \{Gerald Bruce\}",

year = "2006",

month = feb,

day = "1",

doi = "10.1248/cpb.54",

language = "Ingl{\'e}s",

volume = "54",

pages = "278--279",

journal = "Chemical and Pharmaceutical Bulletin",

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TY - JOUR

T1 - Larvicidal, antimycobacterial and antifungal compounds from the bark of the peruvian plant Swartzia polyphylla DC

AU - Rojas, Rosario

AU - Bustamante, Betty

AU - Ventosilla, Palmira

AU - Fernádez, Irma

AU - Caviedes, Luz

AU - Gilman, Robert Henry

AU - Lock, Olga

AU - Hammond, Gerald Bruce

PY - 2006/2/1

Y1 - 2006/2/1

N2 - The 95% ethanol extract of the bark of Swartzia polyphylla DC (Fabaceae) possesses important larvicidal, antimycobacterial and antifungal activity in vitro. Bioassay-guided studies performed on the crude ethanol extract afforded T-cadinol as the larvicidal and anti-Mycobacterium tuberculosis principle, while the antifungal activity of the extract is due to the presence of the flavonoids biochanin A and dihydrobiochanin A.

AB - The 95% ethanol extract of the bark of Swartzia polyphylla DC (Fabaceae) possesses important larvicidal, antimycobacterial and antifungal activity in vitro. Bioassay-guided studies performed on the crude ethanol extract afforded T-cadinol as the larvicidal and anti-Mycobacterium tuberculosis principle, while the antifungal activity of the extract is due to the presence of the flavonoids biochanin A and dihydrobiochanin A.

KW - Antifungal

KW - Antimycobacterial

KW - Biochanin A

KW - Dihydrobiochanin A

KW - Larvicidal

KW - Swartzia polyphylla

UR - https://www.scopus.com/pages/publications/32044456744

U2 - 10.1248/cpb.54

DO - 10.1248/cpb.54

M3 - Artículo

C2 - 16462085

AN - SCOPUS:32044456744

SN - 0009-2363

VL - 54

SP - 278

EP - 279

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 2

ER -

Larvicidal, antimycobacterial and antifungal compounds from the bark of the peruvian plant Swartzia polyphylla DC

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