Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America

Raquel B. De Boni; Bryan E. Shepherd; Beatriz Grinsztejn; Carina Cesar; Claudia Cortés; Denis Padgett; Eduardo Gotuzzo; Pablo F. Belaunzarán-Zamudio; Peter F. Rebeiro; Stephany N. Duda; Catherine C. McGowan

doi:10.1007/s10461-016-1398-6

Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America

Raquel B. De Boni
, Bryan E. Shepherd
, Beatriz Grinsztejn
, Carina Cesar
, Claudia Cortés
, Denis Padgett
, Eduardo Gotuzzo
, Pablo F. Belaunzarán-Zamudio
, Peter F. Rebeiro
, Stephany N. Duda
, Catherine C. McGowan

Instituto Nacional de Infectologia Evandro Chagas (INI)
Vanderbilt University
Fundación Huesped
Fundación Arriarán
Universidad Peruana Cayetano Heredia
Instituto Hondureno de Seguridad Social and Hospital Escuela
Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

36 Citas (Scopus)

Resumen

This cross-sectional study describes substance use prevalence and its association with combination antiretroviral therapy (cART) adherence among 3343 individuals receiving care at HIV clinics in Argentina, Brazil, Chile, Honduras, Mexico, and Peru. A rapid screening tool evaluated self-reported 7-day recall of alcohol, marijuana, cocaine, heroin, and methamphetamine use, and missed cART doses. Overall, 29.3 % individuals reported having ≥1 alcoholic drinks, 5.0 % reported any illicit drug use and 17.0 % reported missed cART doses. In the logistic regression model, compared to no substance use, alcohol use [adjusted odds ratio (AOR) = 2.46, 95 % confidence interval (CI): 1.99–3.05], illicit drug use (AOR = 3.57, 95 % CI: 2.02–6.30), and using both alcohol and illicit drugs (AOR = 4.98, 95 % CI: 3.19–7.79) were associated with missed cART doses. The associations between substance use and likelihood of missing cART doses point to the need of targeting alcohol and illicit drug use to improve adherence among people living with HIV in Latin America.

Idioma original	Inglés
Páginas (desde-hasta)	2692-2699
Número de páginas	8
Publicación	AIDS and behavior
Volumen	20
N.º	11
DOI	https://doi.org/10.1007/s10461-016-1398-6
Estado	Publicada - 1 nov. 2016
Publicado de forma externa	Sí

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

ODS 3: Salud y bienestar

Acceder al documento

10.1007/s10461-016-1398-6

Otros archivos y enlaces

Enlace a la publicación en Scopus

Citar esto

@article{eae409fef5544a8785e2076b30da27b2,

title = "Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America",

abstract = "This cross-sectional study describes substance use prevalence and its association with combination antiretroviral therapy (cART) adherence among 3343 individuals receiving care at HIV clinics in Argentina, Brazil, Chile, Honduras, Mexico, and Peru. A rapid screening tool evaluated self-reported 7-day recall of alcohol, marijuana, cocaine, heroin, and methamphetamine use, and missed cART doses. Overall, 29.3 \% individuals reported having ≥1 alcoholic drinks, 5.0 \% reported any illicit drug use and 17.0 \% reported missed cART doses. In the logistic regression model, compared to no substance use, alcohol use [adjusted odds ratio (AOR) = 2.46, 95 \% confidence interval (CI): 1.99–3.05], illicit drug use (AOR = 3.57, 95 \% CI: 2.02–6.30), and using both alcohol and illicit drugs (AOR = 4.98, 95 \% CI: 3.19–7.79) were associated with missed cART doses. The associations between substance use and likelihood of missing cART doses point to the need of targeting alcohol and illicit drug use to improve adherence among people living with HIV in Latin America.",

keywords = "Adherence, HIV/AIDS, Latin America, Substance use",

author = "\{De Boni\}, \{Raquel B.\} and Shepherd, \{Bryan E.\} and Beatriz Grinsztejn and Carina Cesar and Claudia Cort{\'e}s and Denis Padgett and Eduardo Gotuzzo and Belaunzar{\'a}n-Zamudio, \{Pablo F.\} and Rebeiro, \{Peter F.\} and Duda, \{Stephany N.\} and McGowan, \{Catherine C.\}",

note = "Publisher Copyright: {\textcopyright} 2016, Springer Science+Business Media New York.",

year = "2016",

month = nov,

day = "1",

doi = "10.1007/s10461-016-1398-6",

language = "Ingl{\'e}s",

volume = "20",

pages = "2692--2699",

journal = "AIDS and behavior",

issn = "1573-3254",

number = "11",

}

TY - JOUR

T1 - Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America

AU - De Boni, Raquel B.

AU - Shepherd, Bryan E.

AU - Grinsztejn, Beatriz

AU - Cesar, Carina

AU - Cortés, Claudia

AU - Padgett, Denis

AU - Gotuzzo, Eduardo

AU - Belaunzarán-Zamudio, Pablo F.

AU - Rebeiro, Peter F.

AU - Duda, Stephany N.

AU - McGowan, Catherine C.

PY - 2016/11/1

Y1 - 2016/11/1

N2 - This cross-sectional study describes substance use prevalence and its association with combination antiretroviral therapy (cART) adherence among 3343 individuals receiving care at HIV clinics in Argentina, Brazil, Chile, Honduras, Mexico, and Peru. A rapid screening tool evaluated self-reported 7-day recall of alcohol, marijuana, cocaine, heroin, and methamphetamine use, and missed cART doses. Overall, 29.3 % individuals reported having ≥1 alcoholic drinks, 5.0 % reported any illicit drug use and 17.0 % reported missed cART doses. In the logistic regression model, compared to no substance use, alcohol use [adjusted odds ratio (AOR) = 2.46, 95 % confidence interval (CI): 1.99–3.05], illicit drug use (AOR = 3.57, 95 % CI: 2.02–6.30), and using both alcohol and illicit drugs (AOR = 4.98, 95 % CI: 3.19–7.79) were associated with missed cART doses. The associations between substance use and likelihood of missing cART doses point to the need of targeting alcohol and illicit drug use to improve adherence among people living with HIV in Latin America.

AB - This cross-sectional study describes substance use prevalence and its association with combination antiretroviral therapy (cART) adherence among 3343 individuals receiving care at HIV clinics in Argentina, Brazil, Chile, Honduras, Mexico, and Peru. A rapid screening tool evaluated self-reported 7-day recall of alcohol, marijuana, cocaine, heroin, and methamphetamine use, and missed cART doses. Overall, 29.3 % individuals reported having ≥1 alcoholic drinks, 5.0 % reported any illicit drug use and 17.0 % reported missed cART doses. In the logistic regression model, compared to no substance use, alcohol use [adjusted odds ratio (AOR) = 2.46, 95 % confidence interval (CI): 1.99–3.05], illicit drug use (AOR = 3.57, 95 % CI: 2.02–6.30), and using both alcohol and illicit drugs (AOR = 4.98, 95 % CI: 3.19–7.79) were associated with missed cART doses. The associations between substance use and likelihood of missing cART doses point to the need of targeting alcohol and illicit drug use to improve adherence among people living with HIV in Latin America.

KW - Adherence

KW - HIV/AIDS

KW - Latin America

KW - Substance use

UR - https://www.scopus.com/pages/publications/84964330706

U2 - 10.1007/s10461-016-1398-6

DO - 10.1007/s10461-016-1398-6

M3 - Artículo

C2 - 27091028

AN - SCOPUS:84964330706

SN - 1573-3254

VL - 20

SP - 2692

EP - 2699

JO - AIDS and behavior

JF - AIDS and behavior

IS - 11

ER -

Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America

Resumen

ODS de las Naciones Unidas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto