Thrombin-like activity in snake venoms from Peruvian Bothrops and Lachesis genera

P. Orejuela; A. Zavaleta; M. Salas; N. Marsh

doi:10.1016/0041-0101(91)90212-A

Thrombin-like activity in snake venoms from Peruvian Bothrops and Lachesis genera

P. Orejuela
, A. Zavaleta
, M. Salas
, N. Marsh

Universidad Peruana Cayetano Heredia
Instituto Nacional de Salud del Perú
King’s College London

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

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P. Orejuela, A. Zavaleta, M. Salas and N. Marsh. Thrombin-like activity in snake venoms from Peruvian Bothrops and Lachesis genera. Toxicon 29, 1151-1154, 1991.-Venoms from Lachesis muta muta, Bothrops pictus, B. barnetti, B. atrox and B. hyoprorus coagulate in vitro canine fibrinogen, and both bovine fibrinogen and bovine plasma. B. barnetti and L. muta muta venoms have greater activity on canine fibrinogen and B. atrox and B. hyoprorus venoms, a greater activity on bovine fibrinogen. Gel filtration showed one peak of coagulant activity in all venoms except B. atrox venom which possessed two peaks. The apparent mol. wt of these enzymes ranged from 45,000 to 69,000.

Idioma original	Inglés
Páginas (desde-hasta)	1151-1154
Número de páginas	4
Publicación	Toxicon
Volumen	29
N.º	9
DOI	https://doi.org/10.1016/0041-0101(91)90212-A
Estado	Publicada - 1991

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title = "Thrombin-like activity in snake venoms from Peruvian Bothrops and Lachesis genera",

abstract = "P. Orejuela, A. Zavaleta, M. Salas and N. Marsh. Thrombin-like activity in snake venoms from Peruvian Bothrops and Lachesis genera. Toxicon 29, 1151-1154, 1991.-Venoms from Lachesis muta muta, Bothrops pictus, B. barnetti, B. atrox and B. hyoprorus coagulate in vitro canine fibrinogen, and both bovine fibrinogen and bovine plasma. B. barnetti and L. muta muta venoms have greater activity on canine fibrinogen and B. atrox and B. hyoprorus venoms, a greater activity on bovine fibrinogen. Gel filtration showed one peak of coagulant activity in all venoms except B. atrox venom which possessed two peaks. The apparent mol. wt of these enzymes ranged from 45,000 to 69,000.",

author = "P. Orejuela and A. Zavaleta and M. Salas and N. Marsh",

year = "1991",

doi = "10.1016/0041-0101(91)90212-A",

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T1 - Thrombin-like activity in snake venoms from Peruvian Bothrops and Lachesis genera

AU - Orejuela, P.

AU - Zavaleta, A.

AU - Salas, M.

AU - Marsh, N.

PY - 1991

Y1 - 1991

N2 - P. Orejuela, A. Zavaleta, M. Salas and N. Marsh. Thrombin-like activity in snake venoms from Peruvian Bothrops and Lachesis genera. Toxicon 29, 1151-1154, 1991.-Venoms from Lachesis muta muta, Bothrops pictus, B. barnetti, B. atrox and B. hyoprorus coagulate in vitro canine fibrinogen, and both bovine fibrinogen and bovine plasma. B. barnetti and L. muta muta venoms have greater activity on canine fibrinogen and B. atrox and B. hyoprorus venoms, a greater activity on bovine fibrinogen. Gel filtration showed one peak of coagulant activity in all venoms except B. atrox venom which possessed two peaks. The apparent mol. wt of these enzymes ranged from 45,000 to 69,000.

AB - P. Orejuela, A. Zavaleta, M. Salas and N. Marsh. Thrombin-like activity in snake venoms from Peruvian Bothrops and Lachesis genera. Toxicon 29, 1151-1154, 1991.-Venoms from Lachesis muta muta, Bothrops pictus, B. barnetti, B. atrox and B. hyoprorus coagulate in vitro canine fibrinogen, and both bovine fibrinogen and bovine plasma. B. barnetti and L. muta muta venoms have greater activity on canine fibrinogen and B. atrox and B. hyoprorus venoms, a greater activity on bovine fibrinogen. Gel filtration showed one peak of coagulant activity in all venoms except B. atrox venom which possessed two peaks. The apparent mol. wt of these enzymes ranged from 45,000 to 69,000.

UR - https://www.scopus.com/pages/publications/0025820638

U2 - 10.1016/0041-0101(91)90212-A

DO - 10.1016/0041-0101(91)90212-A

M3 - Artículo

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AN - SCOPUS:0025820638

SN - 0041-0101

VL - 29

SP - 1151

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JO - Toxicon

JF - Toxicon

IS - 9

ER -

Thrombin-like activity in snake venoms from Peruvian Bothrops and Lachesis genera

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